Laura Miozzi

RESEARCH ACTIVITY

In the PhD, I focused my attention on the molecular basis of the interaction between the mycorrhizal fungus Tuber borchii and Cistus. I then investigated the microbial diversity in truffle ground soils and in orchids endophytic fungi.

Since 2004, I focused my attention on bioinformatics, working in the computational biology group at the Dep. of Genetics, Biology and Biochemistry, University of Torino; my activity was mainly focused on development of data-mining approaches for gene functional annotation, based on expression data.

Since 2006, I work as bioinformatics at the IVV, where I study the molecular basis of plant-virus interaction, using both transcriptomic (microarray) and next generation sequencing approaches, with particular attention to the role of small RNAs. My research mainly focuses on the molecular basis of interactions between tomato plants and the viruses TSWV and TYLCSV. I also developed a bioinformatics approach for the functional annotation of tomato genes, based on conserved co-expression among the Solanaceae. I collaborate with the Dep. of Plant Biology, Univ. of Torino to study the effect of mycorrhization on  plant responses to viruses.

 

Publications

  • 2014 - Transcriptomics of the Interaction between the Monopartite Phloem-Limited Geminivirus Tomato Yellow Leaf Curl Sardinia Virus and Solanum lycopersicum Highlights a Role for Plant Hormones, Autophagy and Plant Immune System Fine Tuning during Infection. - Miozzi L., Napoli C., Sardo L., Accotto G.P. - PLoS One, 9: e89951
  • 2013 - The arbuscular mycorrhizal symbiosis attenuates symptom severity and reduces virus concentration in tomato infected by Tomato yellow leaf curl Sardinia virus (TYLCSV) - Maffei G, Miozzi L, Fiorilli V, Novero M, Lanfranco L, Accotto GP. - Mycorrhiza,
  • 2013 - Analysis of small RNAs derived from tomato yellow leaf curl Sardinia virus reveals a cross reaction between the major viral hotspot and the plant host genome - Miozzi L., Pantaleo V., Burgyán J., Accotto G.P., Noris E. - Virus Research, 178:287-296
  • 2013 - Genome-wide identification of viral and host transcripts targeted by viral siRNAs in Vitis vinifera - Miozzi L., Gambino G., Burgyan J. & Pantaleo V. - Molecular plant pathology, 30-43
  • 2012 - Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications - Davino, S., Miozzi L., Panno, S., Rubio, L., Davino, M., Accotto, G.P. - Journal of general virology, 2712-2717
  • 2011 - Arbuscular Mycorrhizal Symbiosis Limits Foliar Transcriptional Responses To Viral Infection And Favors Long-term Virus Accumulation - Miozzi L., Catoni M. Fiorilli V., Mullineaux P.M. , Accotto G.P., Lanfranco L. - Molecular Plant-microbe Interactions (09067J0), volume 24 pag. 1562-1572
  • 2010 - Bacterial And Fungal Communities Associated To Tuber Magnatum-productive Niches - Mello, A. 1 , Miozzi, L. , Vizzini, A. 3, Napoli C. 3, Kowalchuk, G.2 Bonfante, P.1,3 - Plant Biosystems (13410J0), volume 144 pag. 323-332
  • 2010 - The Complete Nucleotide Sequence Of An Isolate Of Tomato Yellow Leaf Curl Sardinia Virus Found In Sicily - Davino S., Miozzi L., Accotto G.P. - Archives Of Virology (15471J0), volume 155 pag. 1539-1542
  • 2010 - Ortom: A Multi-species Approach Based On Conserved Co-expression To Identify Putative Functional Relationships Among Genes In Tomato. - Miozzi L., Provero P., Accotto G.P. - Plant Molecular Biology (05842J0), volume 73 pag. 519-532
  • 2010 - Identification Of Grapevine Micrornas And Their Targets Using High Throughput Sequencing And Degradome Analysis. - Pantaleo V., Szittya G., Moxon S., Miozzi L., Moulton V., Dalmay T. & Burgyan J. - Plant Journal (09659J0), volume x pag. x-x
  • 2010 - Deep Sequencing Analysis Of Viral Short Rnas From An Infected Pinot Noir Grapevine - Pantaleo V., Saldarelli P., Miozzi L. , Giampetruzzi A., Gisel A., Moxon S., Dalmay T., Bisztray G. & Burgyan J. - Virology (95304J0), volume 408 pag. 49-56
  • 2009 - Two New Natural Begomovirus Recombinants Associated With The Tomato Yellow Leaf Curl Disease Co-exist With Parental Viruses In Tomato Epidemics In Italy - Davino S., Napoli C., Dellacroce C., Miozzi L., Noris E., Davino M., Accotto G.P. - Virus Research (06153J0), volume 143 pag. 15-23
  • 2009 - Comparative Analysis Of Expression Profiles In Shoots And Roots Of Tomato Systemically Infected By Tomato Spotted Wilt Virus Reveals Organ-specific Transcriptional Responses - Catoni M., Miozzi L., Fiorilli V., Lanfranco L., Accotto G.P. - Molecular Plant-microbe Interactions (09067J0), volume 22 pag. 1504-1513
  • 2009 - Global And Cell-type Gene Expression Profiles In Tomato Plants Colonized By An Arbuscular Mycorrhyzal Fungus. - Fiorilli V., Catoni M., Miozzi L., Novero M., Accotto G.P., Lanfranco L. - New Phytologist (71720J0), volume 184 pag. 975-987
  • 2008 - Functional Annotation And Identification Of Candidate Disease Genes By Computational Analisys Of Normal Tissue Gene Expression Data - Miozzi, L., Piro, R.m., Rosa, F., Ala, U., Silengo, L., Di Cunto, F., Provero, P. - Plos One (00098NN), Publisher: 3(6)
  • - From root to fruit: RNA-Seq analysis shows that arbuscular mycorrhizal symbiosis may affect tomato fruit metabolism - Inès Zouari, Alessandra Salvioli, Matteo Chialva, Mara Novero, Laura Miozzi, Gian Carlo Tenore, Paolo Bagnaresi and Paola Bonfante - BMC Genomics, 15:221-239