Vitantonio Pantaleo

Fundamental researches on molecular aspects of plant-virus interaction focusing on RNA silencing, viral replication in plants and molecular basis of viral symptoms:

a) molecular characterization of virus-derived smallRNAs acting in RNA silencing-based antiviral defense and in targeting plant mRNAs;

b) identification of plant endogenous small RNAs involved in plant virus interaction;

c) characterization of AGO proteins and complexes involved in antiviral RNA silencing.


Applied researches on the use of RNA silencing-based :


a) non-transgenic strategies for helping plants against viruses:

b) developing protocols and algorithms for identifying novel unknown infectious agent based of viral siRNAs libraries;

c) set-up of in vitro systems able to test the efficacy of synthetic siRNAs against viruses.



  • 2013 - Genome-wide identification of viral and host transcripts targeted by viral siRNAs in Vitis vinifera - Miozzi L., Gambino G., Burgyan J. & Pantaleo V. - Molecular plant pathology, 30-43
  • 2013 - Piccoli RNA interferenti, immunità ai patogeni e applicazioni biotecnologiche - Pantaleo, V. & Barbarossa, L. - Protezione delle colture, 11-19
  • 2013 - Analysis of small RNAs derived from tomato yellow leaf curl Sardinia virus reveals a cross reaction between the major viral hotspot and the plant host genome - Miozzi L., Pantaleo V., Burgyán J., Accotto G.P., Noris E. - Virus Research, 178:287-296
  • 2013 - AGO/RISC-mediated antiviral RNA silencing in a plant in vitro system - J. Schuck, T.Gursinsky, V. Pantaleo, J. Burgyán, S.-E. Behrens - Nucleic Acids Research, 41:5090-5103
  • 2012 - Homology-independent Discovery Of Replicating Pathogenic Circular Rnas By Deep Sequencing And A New Computational Algorithm - Wua Q., Wang Y., Caob M., Pantaleo V., Burgyan J., Wan-Xiang Li, Ding S.W. - Proceedings Of The National Academy Of Sciences Of The United States Of America (79772J0), volume 109 pag. 3938-3943
  • 2011 - A Viral Satellite Rna Induces Yellow Symptoms On Tobacco By Targeting A Gene Involved In Chlorophyll Biosynthesis Using The Rna Silencing Machinery - Shimura H.(1), Pantaleo V., Ishihara T.(1), Myojo N. (1), Inaba J.(1), Sueda K. (1), Burgyan J. & Masuta C.(1) - Plos Pathogens (00412NN), Publisher: 7(5)
  • 2011 - Viral Induction And Suppression Of Rna Silencing In Plants - Shimura H. 1 & Pantaleo V. - Biochimica Et Biophysica Acta (19888J0), volume 1809 pag. 601-612
  • 2011 - Plant Rna Silencing In Viral Defence - V. Pantaleo - Rna Infrastructure And Networks , Publisher: SPRINGER-VERLAG BERLIN
  • 2010 - Structural And Functional Analysis Of Viral Sirnas. - Szittya G, Moxon S, Pantaleo V, Toth G, Rusholme Pilcher Rl, Moulton V, Burgyan J, Dalmay T - Plos Pathogens (00412NN), Publisher: 6
  • 2010 - Identification Of Grapevine Micrornas And Their Targets Using High Throughput Sequencing And Degradome Analysis. - Pantaleo V., Szittya G., Moxon S., Miozzi L., Moulton V., Dalmay T. & Burgyan J. - Plant Journal (09659J0), volume x pag. x-x
  • 2010 - Deep Sequencing Analysis Of Viral Short Rnas From An Infected Pinot Noir Grapevine - Pantaleo V., Saldarelli P., Miozzi L. , Giampetruzzi A., Gisel A., Moxon S., Dalmay T., Bisztray G. & Burgyan J. - Virology (95304J0), volume 408 pag. 49-56
  • 2009 - Rna Silencing: An Antiviral Mechanism. - Csorba, T., Pantaleo, V., Burgyan, J. - Advances In Virus Research - Natural And Engineered Resiatance To Plant Viruse.s , Publisher: Loebenstein, G. & Carr, J.P.
  • 2009 - Deep Sequencing Of Viroid-derived Small Rnas From Grapevine Provides New Insights On The Role Of Rna Silencing In Plant-viroid Interaction. - Navarro, B., Pantaleo, V., Gisel, A., Moxon, S., Dalmay, T., Bisztray, G., Di Serio, F., Burgyan, J. - Plos One (00098NN), Publisher: 4
  • 2009 - Rna Silencing: An Antiviral Mechanism - Csorba T., Pantaleo V., Burgyan J. - Advances In Virus Research (00072S0), volume 75 pag. 35-71
  • 2008 - Virus Associated With Fig Mosaic In Hungary - A. De Stradis, A. Pantaleo, P. Salamon1, A. Minafra, And G.p. Martelli2 - Journal Of Plant Pathology (00077NN), Publisher: 90(3)
  • 2008 - Cymbidium Ringspot Virus Harnesses Rna Silencing To Control The Accumulation Of Virus Parasite Satellite Rna. - Pantaleo, V., Burgyan, J. - Journal Of Virology (62788J0), volume 82 pag. 11851-11858
  • 2007 - Molecular Bases Of Viral Rna Targetin By Viral Small Interfering Rna-programmed Risc - Pantaleo, V,, Szittya, G., Burgyán, J. - Journal Of Virology (62788J0), volume 81(8) pag. 3797-3806
  • 2006 - The Role Of The C-terminal Region Of Olive Latent Virus 1 Coat Protein In Host Systemic Infection. - Pantaleo, V., Grieco, F., Di Franco, A. & Martelli, G.p. - Archives Of Virology (15471J0), volume 151 pag. 1973-1983
  • 2006 - Cytological Analisys Of Saccharomyces Cerevisiae Cell Supporting Cymbidium Ringspot Virus Defective Interfering Rna Replication - Navarro, B., Russo, M., Pantaleo, V. & Rubino, L. - Journal Of General Virology (54890J0), volume 87 pag. 705-714
  • 2006 - Small Rna Binding Is A Common Strategy To Suppress Rna Silencing By Several Viral Suppressors. - Lakatos, L., Csorba, T., Pantaleo, V., Chapman, E.j., Carrington, J.c., Liu, Y.p., Dolja, V.v., Calvino, L.f., Lopez-moya, J.j., & Burgyan, J. - Embo Journal (04123J0), volume 25 pag. 2768-2780
  • 2004 - The P36 And P95 Replicase Proteins Of Carnation Italian Ringspot Virus Cooperate In Stabilizing Defective Interfering Rna. - Pantaleo, V., L. Rubino E M. Russo - Journal Of General Virology (54890J0), volume 85 pag. 2429-2433
  • 2004 - Expression Of Tombusvirus Open Reading Frames 1 And 2 Is Sufficient For The Replication Of Defective Interfering, But Not Of Satellite Rna. - Rubino, L., V. Pantaleo, B. Navarro E M. Russo - Journal Of General Virology (54890J0), volume 85 pag. 3115-3122
  • 2003 - Replication Of Carnation Italian Ringspot Virus Defective Interfering Rna In Saccharomyces Cerevisiae. - Pantaleo V., Rubino L., Russo M. - Journal Of Virology (62788J0), volume 77 pag. 2116-2123
  • 2003 - Graft Incompatibilitty Syndrome In New Zealand Merlot Vines Involves Another Possible Variant Of Glrav-2. - Bonfiglioli R., Edwards F., Hoskins N., Pantaleo V. - Australian & New Zealand Grapegrowers & Winemaker , volume 476 pag. 50-54